Studies and Research

RESEARCH ARTICLE

Clin Ter 2020; 171 (1):e46-52.     doi: 10.7417/CT.2020.2188

CANTORE A ET AL. EFFECTS OF SEA SALT RINSES ON SUBJECTS UNDERGONE TO ORAL SURGERY: A SINGLE BLINDED RANDOMIZED CONTROLLED TRIAL. CLIN TER 2020; 171 (1):E46-52

ABSTRACT

PURPOSE: It has been customary to explain the dentally beneficial effects of xylitol and certain other natural compounds such as lysozyme and sea salt in terms of microbiological effects only.

Several studies have tested the use of natural ingredients, alcohol, and fluoride-free, in mouthwashes. The purpose of this study was to evaluate a combined mouthwash formulation containing natural anti-biofilm agents in oral care wound healing after routine oral surgery (extraction) procedures.

METHODS: Patients were assigned following a blinded randomized controlled trial and divided into two groups, an experimental group (I = 15) and a control (placebo) group (II = 15). Any infectious complications, wound healing, plaque accumulation in the stitches, and presence of trismus and inflammation were evaluated at ten and thirty days after the extraction procedure. Pain and swelling were evaluated using the well-known visual analog scale (VAS) scale throughout the study period following extraction. The mean difference in Pre and Post values was compared among the groups. The change in pre–post score was analyzed using the paired t-test.

RESULTS: An appreciable wound healing was seen in the experimental group when compared to the control sites, with no reported adverse effects. Four weeks postoperative patient satisfaction level, to subjective and objective outcome measurements in documenting the result of a mouthwash treatment, showed an interesting difference between groups.

CONCLUSIONS: Since combined mouthwash formulations, containing natural/bioactive substances, could provide a cheap, safe, and acceptable alternative in oral care, further studies will also be required to study these effects and their mechanism of action in detail. Clin Ter 2020; 171(1):e46-52. doi:10.7417/CT.2020.2188

KEYWORDS: xylitol, lysozyme, seas salt, mouthwash, wound healing, oral surgery

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INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH

ARTICLE

EFfiCACY OF SEA SALT-BASED MOUTHWASH AND XYLITOL IN IMPROVING ORAL HYGIENE AMONG ADOLESCENT POPULATION: A PILOT STUDY

ABSTRACT: The scientific community has definitely demonstrated the importance of the use of mouthwash in daily oral hygiene. In our pilot study, we tested the effectiveness of a novel mouth rinse containing sea salt, xylitol, and lysozyme. Streptococcus mutans (S. mutans) growth, and plaque index in adolescent patients aged 14–17 years, were observed. The bacterial load was investigated by in vitro microbiological analysis; the plaque index was assessed through the O’Leary’s Plaque Control Record (PCR). The study has shown that the use of a sea salt-based mouthwash in daily oral hygiene reduces the bacterial levels of S. mutans (p < 0.01) linked to the combined action of xylitol and lysozyme, together with the action of sea salt. Our preliminary data confirm and improve the main results reported in the scientific literature on the importance of the use of xylitol, lysozyme, and sea salt in oral health.

KEYWORDS: xylitol; sea salt; lysozyme; plaque index; oral health; Streptococcus mutans; clinical micro-biology

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10.5005/jp-journals-10029-1108

RESEARCH ARTICLE

A CLINICAL PILOT STUDY TO EVALUATE THE EFFICACY OF SEA SALT-BASED ORAL RINSE IN GINGIVITIS PATIENTS

ABSTRACT

AIM: This pilot study aimed to evaluate the efficacy of sea salt-based oral rinse as an adjunct with conventional oral hygiene measures in gingivitis patients in terms of clinical parameters.

MATERIALS AND METHODS: A total of 30 gingivitis patients between the ages of 18 and 55 were enrolled in the study and divided into two categories. Clinical parameters were recorded before phase one therapy, and subjects were put on different oral hygiene regimes with and without sea salt-based mouth rinse. At baseline and 3^rd month, subjects were evaluated.

RESULTS: The results of this study showed that there was a significant decrease in clinical parameters from baseline to 3 months in both groups (p < 0.01). The subjects under groups using sea Salt-based mouthwash showed a highly significant under groups using conventional toothbrushing only.

CONCLUSION: Thus, we can conclude that long-term regular use of sea salt-based products seems to be more beneficial.

KEYWORDS: Gingivitis, Mouth rinse, Sea salt.

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International Journal of Biomedical and Advance Research

2018; 9(4): 167-170.

EFFECTS OF SEA SALT BASED ORAL RINSE ON STREPTOCOCCUS MUTANS LEVEL AND ORAL ECOLOGY IN GINGIVITIS SUBJECTS WITH HIGH CARIES SUSCEPTIBILITY: A RANDOMIZED CLINICAL STUDY

ABSTRACT

BACKGROUND: The etiologic role of a pathogenic dental plaque biofilm in the development of gingivitis and dental caries is well documented. This study evaluates the rationale for incorporating sea salt-based mouth rinse into a daily oral hygiene regimen along with mechanical plaque control methods on gingival inflammation and caries susceptibility level in mild to moderate gingivitis patients.

METHODS: A prospective, double-blinded, randomized parallel-group controlled study involving 40 subjects was conducted to assess efficacy and safety. Subjects were randomized to receive either the study rinse (H2Ocean) or a water-only preparation. The oral hygiene index (OHI) and S. Mutans Level were measured at baseline and the end of the study period.

RESULTS: Sea salt mouth rinse was significantly better than the control, concerning both the change in OHI score by 28.89% and S. mutans level by 35%.  No adverse effects were noted in any of the study groups.

CONCLUSION: Sea Salt mouth rinse is a safe and effective treatment for preventing the development of gingival inflammation and S. mutans levels in the mild to moderate gingivitis population. Further research is needed to evaluate its long-term effects.

KEYWORDS: Sea Salt, Plaque, S. mutans, Dental Caries.